Medscape: Biologic Differences in Breast Cancer: An Expert Interview With Dr. Lisa Carey.
"Clinicians who treat women with breast cancer have long recognized wide variations in tumor behavior. Initial attempts to characterize differences among breast tumors and to use them as a basis for determining appropriate treatment strategies focused on hormone expression (ie, estrogen and/or progesterone) and later on overexpression of HER2/neu. However, it was not until genomic technology developed sufficiently to examine thousands of molecular markers simultaneously that a more granular approach to such research became possible.
Interesting interview. Understanding the genetic basis for differences in tumor behavior will provide great insight into successful treatments.
The Wall Street Journal: 