TheScientist present their 2009 in review (+as a PDF file) an interesting and eventful year!
It's hard to pick the most significant event, but it might well be the first; in January the FDA approved the first-ever clinical trial of a human embryonic stem cell-based therapy. (They subsequently held it in August, but still.) Then in February the U.S. Congress approved the $789B recovery bill, including a number of provisions for improving health care and grants to the NIH and NSF. Wow.
And who knows what 2010 will bring?
(my vote would be - ever increasing adoption of digital pathology :)

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